Friday, December 25, 2009

Classification of hormone by general mechanism of action

1. Group 1. Hormones that bind to intracellular receptors

2. Group 2. Hormones that bind to cell surface receptors
a) Second messenger is c AMP
Eg. ACTH, ADH, PTH, TSH, glucagon
b) Second messenger is c GMP Eg. ANP, NO
c) Second messenger is calcium or phosphoinocitol or both Eg.Ach, α ADRENERGIC, TRH
d) Second messenger is a kinase or phosphatase cascade Eg. GROWTH FACTORS, INSULIN

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